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Design and synthesis of fluorescent activity probes for protein phosphatases

Protein phosphatases act in concert with protein kinases to regulate and maintain the phosphoproteome. However, the catalog of chemical tools to directly monitor the enzymatic activity of phosphatases has lagged behind their kinase counterparts. In this chapter, we provide protocols for repurposing...

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Bibliografiske detaljer
Udgivet i:Methods Enzymol
Main Authors: Casey, Garrett R., Beck, Jon R., Stains, Cliff l.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567983/
https://ncbi.nlm.nih.gov/pubmed/31155057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.02.002
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