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Design and synthesis of fluorescent activity probes for protein phosphatases

Protein phosphatases act in concert with protein kinases to regulate and maintain the phosphoproteome. However, the catalog of chemical tools to directly monitor the enzymatic activity of phosphatases has lagged behind their kinase counterparts. In this chapter, we provide protocols for repurposing...

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Detalhes bibliográficos
Publicado no:Methods Enzymol
Main Authors: Casey, Garrett R., Beck, Jon R., Stains, Cliff l.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567983/
https://ncbi.nlm.nih.gov/pubmed/31155057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.02.002
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