Deletion of discoidin domain receptor 2 attenuates renal interstitial fibrosis in a murine unilateral ureteral obstruction model

Background: Renal interstitial fibrosis is a common pathway of chronic kidney disease to end-stage renal disease, which is characterized by an imbalance between the synthesis and degradation of the collagen-rich extracellular matrix (ECM). While, discoidin domain receptor 2 (DDR2) can be activated w...

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Foilsithe in:Ren Fail
Main Authors: Li, Xi’an, Bu, Xin, Yan, Fei, Wang, Fuli, Wei, Di, Yuan, Jiarui, Zheng, Wanxiang, Su, Jin, Yuan, Jianlin
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2019
Ábhair:
Laboratory Study
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567249/
https://ncbi.nlm.nih.gov/pubmed/31169440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/0886022X.2019.1621759
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