Deletion of Akt1 Promotes Kidney Fibrosis in a Murine Model of Unilateral Ureteral Obstruction

We investigated the role of Akt1, one of the three isoforms of Akt, in renal fibrosis using the murine model of unilateral ureteral obstruction (UUO). We subjected wild type and Akt1(−/−) mice to UUO. The Akt1 gene was silenced in vitro using short hairpin RNA delivered via a lentiviral vector in hu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Kim, Il Young, Lee, Min Young, Park, Mi Wha, Seong, Eun Young, Lee, Dong Won, Lee, Soo Bong, Bae, Sun Sik, Kim, Sang Soo, Song, Sang Heon
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7707954/
https://ncbi.nlm.nih.gov/pubmed/33299873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/6143542
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados