Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation

Non-alcoholic steatohepatitis (NASH) is a progressive, chronic, liver disease whose prevalence is growing worldwide. Despite several agents being under development for treating NASH, there are no drugs currently approved. The Farnesoid-x-receptor (FXR) and the G-protein coupled bile acid receptor 1...

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書誌詳細
出版年:Nutrients
主要な著者: Carino, Adriana, Marchianò, Silvia, Biagioli, Michele, Fiorucci, Chiara, Zampella, Angela, Monti, Maria Chiara, Morretta, Elva, Bordoni, Martina, Di Giorgio, Cristina, Roselli, Rosalinda, Ricci, Patrizia, Distrutti, Eleonora, Fiorucci, Stefano
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567134/
https://ncbi.nlm.nih.gov/pubmed/31117231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu11051132
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