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Carbon metabolism modulates the efficacy of drugs targeting the cytochrome bc(1):aa(3) in Mycobacterium tuberculosis
The influence of carbon metabolism on oxidative phosphorylation is poorly understood in mycobacteria. M. tuberculosis expresses two respiratory terminal oxidases, the cytochrome bc(1):aa(3) and the cytochrome bd oxidase, which are jointly required for oxidative phosphorylation and mycobacterial viab...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6565617/ https://ncbi.nlm.nih.gov/pubmed/31197236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44887-9 |
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