Subtypes of Barrett’s Esophagus and Esophageal Adenocarcinoma Based on Genome-wide Methylation Analysis

OBJECTIVE: To determine if DNA methylation subtypes exist in esophageal adenocarcinoma (EAC) and its precursor Barrett’s esophagus (BE). DESIGN: We performed genome-wide DNA methylation profiling on samples of non-dysplastic BE from cancer-free patients (N=59), EAC (N=23), normal squamous esophagus...

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Publicado en:Gut
Autores principales: Yu, Ming, Maden, Sean, Stachler, Matthew, Kaz, Andrew M., Ayers, Jessica, Guo, Yuna, Carter, Kelly T., Willbanks, Amber, Heinzerling, Tai J., O’Leary, Rachele M, Xu, Xinsen, Bass, Adam, Chandar, Apoorva K., Chak, Amitabh, Elliot, Robin, Willis, Joseph E., Markowitz, Sanford D., Grady, William M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565505/
https://ncbi.nlm.nih.gov/pubmed/29884612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2017-314544
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