Subtypes of Barrett’s Esophagus and Esophageal Adenocarcinoma Based on Genome-wide Methylation Analysis

OBJECTIVE: To determine if DNA methylation subtypes exist in esophageal adenocarcinoma (EAC) and its precursor Barrett’s esophagus (BE). DESIGN: We performed genome-wide DNA methylation profiling on samples of non-dysplastic BE from cancer-free patients (N=59), EAC (N=23), normal squamous esophagus...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Yu, Ming, Maden, Sean, Stachler, Matthew, Kaz, Andrew M., Ayers, Jessica, Guo, Yuna, Carter, Kelly T., Willbanks, Amber, Heinzerling, Tai J., O’Leary, Rachele M, Xu, Xinsen, Bass, Adam, Chandar, Apoorva K., Chak, Amitabh, Elliot, Robin, Willis, Joseph E., Markowitz, Sanford D., Grady, William M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565505/
https://ncbi.nlm.nih.gov/pubmed/29884612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2017-314544
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