Global DNA methylation patterns in Barrett’s esophagus, dysplastic Barrett’s, and esophageal adenocarcinoma are associated with BMI, gender, and tobacco use

BACKGROUND: The risk of developing Barrett’s esophagus (BE) and/or esophageal adenocarcinoma (EAC) is associated with specific demographic and behavioral factors, including gender, obesity/elevated body mass index (BMI), and tobacco use. Alterations in DNA methylation, an epigenetic modification tha...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Kaz, Andrew M., Wong, Chao-Jen, Varadan, Vinay, Willis, Joseph E., Chak, Amitabh, Grady, William M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082363/
https://ncbi.nlm.nih.gov/pubmed/27795744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0273-7
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