Global DNA methylation patterns in Barrett’s esophagus, dysplastic Barrett’s, and esophageal adenocarcinoma are associated with BMI, gender, and tobacco use

BACKGROUND: The risk of developing Barrett’s esophagus (BE) and/or esophageal adenocarcinoma (EAC) is associated with specific demographic and behavioral factors, including gender, obesity/elevated body mass index (BMI), and tobacco use. Alterations in DNA methylation, an epigenetic modification tha...

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Vydáno v:Clin Epigenetics
Hlavní autoři: Kaz, Andrew M., Wong, Chao-Jen, Varadan, Vinay, Willis, Joseph E., Chak, Amitabh, Grady, William M.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082363/
https://ncbi.nlm.nih.gov/pubmed/27795744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0273-7
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