Subtypes of Barrett’s Esophagus and Esophageal Adenocarcinoma Based on Genome-wide Methylation Analysis

OBJECTIVE: To determine if DNA methylation subtypes exist in esophageal adenocarcinoma (EAC) and its precursor Barrett’s esophagus (BE). DESIGN: We performed genome-wide DNA methylation profiling on samples of non-dysplastic BE from cancer-free patients (N=59), EAC (N=23), normal squamous esophagus...

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Publicat a:Gut
Autors principals: Yu, Ming, Maden, Sean, Stachler, Matthew, Kaz, Andrew M., Ayers, Jessica, Guo, Yuna, Carter, Kelly T., Willbanks, Amber, Heinzerling, Tai J., O’Leary, Rachele M, Xu, Xinsen, Bass, Adam, Chandar, Apoorva K., Chak, Amitabh, Elliot, Robin, Willis, Joseph E., Markowitz, Sanford D., Grady, William M.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565505/
https://ncbi.nlm.nih.gov/pubmed/29884612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2017-314544
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