Exploring E-cadherin-peptidomimetics interaction using NMR and computational studies

Cadherins are homophilic cell-cell adhesion molecules whose aberrant expression has often been shown to correlate with different stages of tumor progression. In this work, we investigate the interaction of two peptidomimetic ligands with the extracellular portion of human E-cadherin using a combinat...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Main Authors: Civera, Monica, Vasile, Francesca, Potenza, Donatella, Colombo, Cinzia, Parente, Sara, Vettraino, Chiara, Prosdocimi, Tommaso, Parisini, Emilio, Belvisi, Laura
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2019
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6564044/
https://ncbi.nlm.nih.gov/pubmed/31158220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007041
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