Structure-Based Virtual Screening Allows the Identification of Efficient Modulators of E-Cadherin-Mediated Cell–Cell Adhesion

Cadherins are a large family of transmembrane calcium-dependent cell adhesion proteins that orchestrate adherens junction formation and are crucially involved in tissue morphogenesis. Due to their important role in cancer development and metastasis, cadherins can be considered attractive targets for...

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Udgivet i:Int J Mol Sci
Main Authors: Dalle Vedove, Andrea, Falchi, Federico, Donini, Stefano, Dobric, Aurelie, Germain, Sebastien, Di Martino, Giovanni Paolo, Prosdocimi, Tommaso, Vettraino, Chiara, Torretta, Archimede, Cavalli, Andrea, Rigot, Veronique, André, Frederic, Parisini, Emilio
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678102/
https://ncbi.nlm.nih.gov/pubmed/31373305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20143404
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