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Structure-Based Virtual Screening Allows the Identification of Efficient Modulators of E-Cadherin-Mediated Cell–Cell Adhesion

Cadherins are a large family of transmembrane calcium-dependent cell adhesion proteins that orchestrate adherens junction formation and are crucially involved in tissue morphogenesis. Due to their important role in cancer development and metastasis, cadherins can be considered attractive targets for...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Dalle Vedove, Andrea, Falchi, Federico, Donini, Stefano, Dobric, Aurelie, Germain, Sebastien, Di Martino, Giovanni Paolo, Prosdocimi, Tommaso, Vettraino, Chiara, Torretta, Archimede, Cavalli, Andrea, Rigot, Veronique, André, Frederic, Parisini, Emilio
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678102/
https://ncbi.nlm.nih.gov/pubmed/31373305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20143404
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