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The X-ray structure of human P-cadherin EC1-EC2 in a closed conformation provides insight into the type I cadherin dimerization pathway

Cadherins are a large family of calcium-dependent proteins that mediate cellular adherens junction formation and tissue morphogenesis. To date, the most studied cadherins are those classified as classical, which are further divided into type I or type II depending on selected sequence features. Unli...

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Dettagli Bibliografici
Pubblicato in:Acta Crystallogr F Struct Biol Commun
Autori principali: Dalle Vedove, Andrea, Lucarelli, Anna Paola, Nardone, Valentina, Matino, Angelica, Parisini, Emilio
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388168/
https://ncbi.nlm.nih.gov/pubmed/25849494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15003878
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