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Cell cycle-related kinase regulates mammalian eye development through positive and negative regulation of the Hedgehog pathway
Cell cycle-related kinase (CCRK) is a conserved regulator of ciliogenesis whose loss in mice leads to a wide range of developmental defects, including exencephaly, preaxial polydactyly, skeletal abnormalities, and microphthalmia. Here, we investigate the role of CCRK in mouse eye development. Ccrk m...
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| Publicado no: | Dev Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6563835/ https://ncbi.nlm.nih.gov/pubmed/29166577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2017.10.022 |
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