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Cell Cycle-Related Kinase (CCRK) regulates ciliogenesis and Hedgehog signaling in mice

The Hedgehog (Hh) signaling pathway plays a key role in cell fate specification, proliferation, and survival during mammalian development. Cells require a small organelle, the primary cilium, to respond properly to Hh signals and the key regulators of Hh signal transduction exhibit dynamic localizat...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Snouffer, Ashley, Brown, Desmond, Lee, Hankyu, Walsh, Jonathon, Lupu, Floria, Norman, Ryan, Lechtreck, Karl, Ko, Hyuk Wan, Eggenschwiler, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574612/
https://ncbi.nlm.nih.gov/pubmed/28817564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006912
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