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Proper ciliary assembly is critical for restricting Hedgehog signaling during early eye development in mice

Patterning of the vertebrate eye into optic stalk, retinal pigment epithelium (RPE) and neural retina (NR) territories relies on a number of signaling pathways, but how these signals are interpreted by optic progenitors is not well understood. The primary cilium is a microtubule-based organelle that...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Burnett, Jacob B., Lupu, Floria I., Eggenschwiler, Jonathan T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544053/
https://ncbi.nlm.nih.gov/pubmed/28778798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2017.07.012
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