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Adeno-Associated Virus VP1u Exhibits Protease Activity

Adeno-associated viruses (AAVs) are being developed for gene delivery applications, with more than 100 ongoing clinical trials aimed at the treatment of monogenic diseases. In this study, the unique N-terminus of AAV capsid viral protein 1 (VP1u), containing a canonical group XIII PLA(2) enzyme doma...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Kurian, Justin J., Lakshmanan, Renuk, Chmely, William M., Hull, Joshua A., Yu, Jennifer C., Bennett, Antonette, McKenna, Robert, Agbandje-McKenna, Mavis
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563295/
https://ncbi.nlm.nih.gov/pubmed/31035643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11050399
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