RYR1 and CACNA1S genetic variants identified with statin-associated muscle symptoms

AIM: To examine the genetic differences between subjects with statin-associated muscle symptoms and statin-tolerant controls. MATERIALS & METHODS: Next-generation sequencing was used to characterize the exomes of 76 subjects with severe statin-associated muscle symptoms and 50 statin-tolerant co...

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Publicado en:Pharmacogenomics
Autores principales: Isackson, Paul J, Wang, Jianxin, Zia, Mohammad, Spurgeon, Paul, Levesque, Adrian, Bard, Jonathan, James, Smitha, Nowak, Norma, Lee, Tae Keun, Vladutiu, Georgirene D
Formato: Artigo
Lenguaje:Inglês
Publicado: Future Medicine Ltd 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563124/
https://ncbi.nlm.nih.gov/pubmed/30325262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs-2018-0106
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