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Next Generation Sequencing of RYR1 and CACNA1S in Malignant Hyperthermia and Exertional Heat Illness

BACKGROUND: Variants in RYR1 are associated with the majority of cases of malignant hyperthermia (MH), a form of heat illness pharmacogenetically triggered by general anesthetics, and they have also been associated with exertional heat illness. CACNA1S has also been implicated in MH. We applied a ta...

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Detalhes bibliográficos
Publicado no:Anesthesiology
Main Authors: Fiszer, Dorota, Shaw, Marie-Anne, Fisher, Nickla A., Carr, Ian M., Gupta, Pawan K., Watkins, Elizabeth J., de Sa, Daniel Roiz, Kim, Jerry H., Hopkins, Philip M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472733/
https://ncbi.nlm.nih.gov/pubmed/25658027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000610
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