Association of SLCO1B1 c.521T>C (rs4149056) with Discontinuation of Atorvastatin Due to Statin-Associated Muscle Symptoms

The most common adverse drug reaction from statins are statin-associated muscle symptoms (SAMS), such as muscle pain, weakness, and/or elevations in serum creatine kinase levels. All statins are substrates of the organic anion transporter 1B1 (OATP1B1; gene:SLCO1B1), albeit to different degrees. A g...

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Vydáno v:Pharmacogenet Genomics
Hlavní autoři: LINSKEY, DEREK W., ENGLISH, JOSEPH D., PERRY, DANIEL A., OCHS-BALCOM, HEATHER M., MA, CHANGXING, ISACKSON, PAUL J., VLADUTIU, GEORGIRENE D., LUZUM, JASMINE A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062056/
https://ncbi.nlm.nih.gov/pubmed/32453264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000412
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