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Association of SLCO1B1 c.521T>C (rs4149056) with Discontinuation of Atorvastatin Due to Statin-Associated Muscle Symptoms
The most common adverse drug reaction from statins are statin-associated muscle symptoms (SAMS), such as muscle pain, weakness, and/or elevations in serum creatine kinase levels. All statins are substrates of the organic anion transporter 1B1 (OATP1B1; gene:SLCO1B1), albeit to different degrees. A g...
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| Publicado en: | Pharmacogenet Genomics |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8062056/ https://ncbi.nlm.nih.gov/pubmed/32453264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000412 |
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