Bayesian modeling to predict malignant hyperthermia susceptibility and pathogenicity of RYR1, CACNA1S and STAC3 variants

AIM: Identify variants in RYR1, CACNA1S and STAC3, and predict malignant hyperthermia (MH) pathogenicity using Bayesian statistics in individuals clinically treated as MH susceptible (MHS). MATERIALS & METHODS: Whole exome sequencing including RYR1, CACNA1S and STAC3 performed on 64 subjects wit...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Pharmacogenomics
Main Authors: Sadhasivam, Senthilkumar, Brandom, Barbara W, Henker, Richard A, McAuliffe, John J
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006767/
https://ncbi.nlm.nih.gov/pubmed/31559918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs-2019-0055
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados