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Effects of genetic variability on rifampicin and isoniazid pharmacokinetics in South African patients with recurrent tuberculosis
AIM: We report the prevalence and effect of genetic variability on pharmacokinetic parameters of isoniazid and rifampicin. MATERIALS & METHODS: Genotypes for SLCO1B1, NAT2, PXR, ABCB1 and UGT1A genes were determined using a TaqMan(®) Genotyping OpenArray™. Nonlinear mixed-effects models were use...
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| 出版年: | Pharmacogenomics |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Future Medicine Ltd
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6562923/ https://ncbi.nlm.nih.gov/pubmed/30767706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs-2018-0166 |
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