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Effect of genetic variation in UGT1A and ABCB1 on moxifloxacin pharmacokinetics in South African patients with tuberculosis
AIM: We assessed the effect of genetic variability in UGT1A and ABCB1 genes on moxifloxacin pharmacokinetics. METHODS: Genotypes for selected UGT1A and ABCB1 SNPs were determined using a TaqMan(®) Genotyping OpenArray(™) and high-resolution melt analysis for rs8175347. A nonlinear mixed-effects mode...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Pharmacogenomics |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Future Medicine Ltd
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5753622/ https://ncbi.nlm.nih.gov/pubmed/29210323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs-2017-0144 |
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