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Endosomal escape and cytosolic penetration of macromolecules mediated by synthetic delivery agents

Cell delivery reagents often exploit the endocytic pathway as a route of cell entry. Once endocytosed, these reagents must overcome endosomal entrapment to insure the release of their macromolecular cargos into the cytosol of cells. In this review, we describe several examples of prototypical synthe...

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Detalles Bibliográficos
Publicado en:Bioconjug Chem
Main Authors: Brock, Dakota J., Kondow-McConaghy, Helena M., Hager, Elizabeth C., Pellois, Jean-Philippe
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561124/
https://ncbi.nlm.nih.gov/pubmed/30462487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.8b00799
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