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Potent Enhancement of HIV-1 Replication by Nef in the Absence of SERINC3 and SERINC5

It has recently emerged that HIV-1 Nef counteracts the antiviral host proteins SERINC3 and SERINC5. In particular, SERINC5 inhibits the infectivity of progeny virions when incorporated. SERINC3 and SERINC5 are also counteracted by the unrelated murine leukemia virus glycosylated Gag (glycoGag) prote...

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Détails bibliographiques
Publié dans:mBio
Auteurs principaux: Wu, Yuanfei, Olety, Balaji, Weiss, Eric R., Popova, Elena, Yamanaka, Hikaru, Göttlinger, Heinrich
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561029/
https://ncbi.nlm.nih.gov/pubmed/31186327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01071-19
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