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SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef
HIV-1 Nef and the unrelated murine leukemia virus glycoGag strongly enhance the infectivity of HIV-1 virions produced in certain cell types in a clathrin-dependent manner. Here we show that Nef and glycoGag prevent the incorporation of the multipass transmembrane proteins SERINC3 and SERINC5 into HI...
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| Publicado no: | Nature |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4600458/ https://ncbi.nlm.nih.gov/pubmed/26416733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature15400 |
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