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Potent Enhancement of HIV-1 Replication by Nef in the Absence of SERINC3 and SERINC5

It has recently emerged that HIV-1 Nef counteracts the antiviral host proteins SERINC3 and SERINC5. In particular, SERINC5 inhibits the infectivity of progeny virions when incorporated. SERINC3 and SERINC5 are also counteracted by the unrelated murine leukemia virus glycosylated Gag (glycoGag) prote...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Wu, Yuanfei, Olety, Balaji, Weiss, Eric R., Popova, Elena, Yamanaka, Hikaru, Göttlinger, Heinrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561029/
https://ncbi.nlm.nih.gov/pubmed/31186327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01071-19
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