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Potent Enhancement of HIV-1 Replication by Nef in the Absence of SERINC3 and SERINC5

It has recently emerged that HIV-1 Nef counteracts the antiviral host proteins SERINC3 and SERINC5. In particular, SERINC5 inhibits the infectivity of progeny virions when incorporated. SERINC3 and SERINC5 are also counteracted by the unrelated murine leukemia virus glycosylated Gag (glycoGag) prote...

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Detalles Bibliográficos
Publicado en:mBio
Main Authors: Wu, Yuanfei, Olety, Balaji, Weiss, Eric R., Popova, Elena, Yamanaka, Hikaru, Göttlinger, Heinrich
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561029/
https://ncbi.nlm.nih.gov/pubmed/31186327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01071-19
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