GREACE-assisted adaptive laboratory evolution in endpoint fermentation broth enhances lysine production by Escherichia coli

BACKGROUND: Late-stage fermentation broth contains high concentrations of target chemicals. Additionally, it contains various cellular metabolites which have leaked from lysed cells, which would exert multifactorial stress to industrial hyperproducers and perturb both cellular metabolism and product...

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Veröffentlicht in:Microb Cell Fact
Hauptverfasser: Wang, Xiaowei, Li, Qinggang, Sun, Cunmin, Cai, Zhen, Zheng, Xiaomei, Guo, Xuan, Ni, Xiaomeng, Zhou, Wenjuan, Guo, Yanmei, Zheng, Ping, Chen, Ning, Sun, Jibin, Li, Yin, Ma, Yanhe
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6560909/
https://ncbi.nlm.nih.gov/pubmed/31186003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-019-1153-6
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