GREACE-assisted adaptive laboratory evolution in endpoint fermentation broth enhances lysine production by Escherichia coli

BACKGROUND: Late-stage fermentation broth contains high concentrations of target chemicals. Additionally, it contains various cellular metabolites which have leaked from lysed cells, which would exert multifactorial stress to industrial hyperproducers and perturb both cellular metabolism and product...

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Enregistré dans:
Détails bibliographiques
Publié dans:Microb Cell Fact
Auteurs principaux: Wang, Xiaowei, Li, Qinggang, Sun, Cunmin, Cai, Zhen, Zheng, Xiaomei, Guo, Xuan, Ni, Xiaomeng, Zhou, Wenjuan, Guo, Yanmei, Zheng, Ping, Chen, Ning, Sun, Jibin, Li, Yin, Ma, Yanhe
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6560909/
https://ncbi.nlm.nih.gov/pubmed/31186003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-019-1153-6
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