GREACE-assisted adaptive laboratory evolution in endpoint fermentation broth enhances lysine production by Escherichia coli

BACKGROUND: Late-stage fermentation broth contains high concentrations of target chemicals. Additionally, it contains various cellular metabolites which have leaked from lysed cells, which would exert multifactorial stress to industrial hyperproducers and perturb both cellular metabolism and product...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Wang, Xiaowei, Li, Qinggang, Sun, Cunmin, Cai, Zhen, Zheng, Xiaomei, Guo, Xuan, Ni, Xiaomeng, Zhou, Wenjuan, Guo, Yanmei, Zheng, Ping, Chen, Ning, Sun, Jibin, Li, Yin, Ma, Yanhe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6560909/
https://ncbi.nlm.nih.gov/pubmed/31186003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-019-1153-6
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