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Mutations in Na(V)1.5 Reveal Calcium-Calmodulin Regulation of Sodium Channel
Mutations in the SCN5A gene, encoding the cardiac voltage-gated sodium channel Na(V)1.5, are associated with inherited cardiac arrhythmia and conduction disease. Ca(2+)-dependent mechanisms and the involvement of β-subunit (Na(V)β) in Na(V)1.5 regulation are not fully understood. A patient with seve...
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| Опубликовано в: : | Front Physiol |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6560087/ https://ncbi.nlm.nih.gov/pubmed/31231243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00700 |
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