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Biochemical characterization and structural basis of reactivity and regioselectivity differences of Burkholderia thailandensis and Burkholderia glumae 1,6-didesmethyltoxoflavin N-methyltransferase

Burkholderia glumae converts the guanine base of guanosine triphosphate into an azapteridine and methylates both the pyrimidine and triazine rings to make toxoflavin. Strains of Burkholderia thailandensis and Burkholderia pseudomallei have a gene cluster encoding seven putative biosynthetic enzymes...

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Dades bibliogràfiques
Publicat a:Biochemistry
Autors principals: Fenwick, Michael K., Almabruk, Khaled H., Ealick, Steven E., Begley, Tadhg P., Philmus, Benjamin
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6559721/
https://ncbi.nlm.nih.gov/pubmed/28665591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00476
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