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Toxoflavin Lyase Requires a Novel 1-His-2-Carboxylate Facial Triad,
High resolution crystal structures are reported for apo, holo, and substrate-bound forms of a toxoflavin-degrading metalloenzyme (TflA). In addition, the degradation reaction is shown to be dependent on oxygen, Mn(II), and dithiothreitol in vitro. Despite its low sequence identity with proteins of k...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3035768/ https://ncbi.nlm.nih.gov/pubmed/21166463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101741v |
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