A chemical kinetic basis for measuring translation initiation and elongation rates from ribosome profiling data

Analysis methods based on simulations and optimization have been previously developed to estimate relative translation rates from next-generation sequencing data. Translation involves molecules and chemical reactions, hence bioinformatics methods consistent with the laws of chemistry and physics are...

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Détails bibliographiques
Publié dans:PLoS Comput Biol
Auteurs principaux: Sharma, Ajeet K., Sormanni, Pietro, Ahmed, Nabeel, Ciryam, Prajwal, Friedrich, Ulrike A., Kramer, Günter, O’Brien, Edward P.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6559674/
https://ncbi.nlm.nih.gov/pubmed/31120880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007070
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