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Hepatocyte-macrophage acetoacetate shuttle protects against tissue fibrosis
Metabolic plasticity has been linked to polarized macrophage function, but mechanisms connecting specific fuels to tissue macrophage function remain unresolved. Here we apply a stable isotope tracing, mass spectrometry-based untargeted metabolomics approach to reveal the metabolome penetrated by hep...
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| Publicado no: | Cell Metab |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6559243/ https://ncbi.nlm.nih.gov/pubmed/30449686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2018.10.015 |
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