Diminished ketone interconversion, hepatic TCA cycle flux, and glucose production in D-β-hydroxybutyrate dehydrogenase hepatocyte-deficient mice

OBJECTIVE: Throughout the last decade, interest has intensified in intermittent fasting, ketogenic diets, and exogenous ketone therapies as prospective health-promoting, therapeutic, and performance-enhancing agents. However, the regulatory roles of ketogenesis and ketone metabolism on liver homeost...

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Publicat a:Mol Metab
Autors principals: Stagg, David B., Gillingham, Jacob R., Nelson, Alisa B., Lengfeld, Justin E., d’Avignon, D. André, Puchalska, Patrycja, Crawford, Peter A.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259407/
https://ncbi.nlm.nih.gov/pubmed/34116232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2021.101269
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