Hepatic ketogenic insufficiency reprograms hepatic glycogen metabolism and the lipidome

While several molecular targets are under consideration, mechanistic underpinnings of the transition from uncomplicated nonalcoholic fatty liver disease (NAFLD) to nonalcoholic steatohepatitis (NASH) remain unresolved. Here we apply multiscale chemical profiling technologies to mouse models of deran...

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Bibliografiske detaljer
Udgivet i:JCI Insight
Main Authors: d’Avignon, D. André, Puchalska, Patrycja, Ercal, Baris, Chang, YingJu, Martin, Shannon E., Graham, Mark J., Patti, Gary J., Han, Xianlin, Crawford, Peter A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124396/
https://ncbi.nlm.nih.gov/pubmed/29925686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99762
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