Hepatic ketogenic insufficiency reprograms hepatic glycogen metabolism and the lipidome

While several molecular targets are under consideration, mechanistic underpinnings of the transition from uncomplicated nonalcoholic fatty liver disease (NAFLD) to nonalcoholic steatohepatitis (NASH) remain unresolved. Here we apply multiscale chemical profiling technologies to mouse models of deran...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: d’Avignon, D. André, Puchalska, Patrycja, Ercal, Baris, Chang, YingJu, Martin, Shannon E., Graham, Mark J., Patti, Gary J., Han, Xianlin, Crawford, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124396/
https://ncbi.nlm.nih.gov/pubmed/29925686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99762
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