Hepatic ketogenic insufficiency reprograms hepatic glycogen metabolism and the lipidome

While several molecular targets are under consideration, mechanistic underpinnings of the transition from uncomplicated nonalcoholic fatty liver disease (NAFLD) to nonalcoholic steatohepatitis (NASH) remain unresolved. Here we apply multiscale chemical profiling technologies to mouse models of deran...

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Bibliografische gegevens
Gepubliceerd in:JCI Insight
Hoofdauteurs: d’Avignon, D. André, Puchalska, Patrycja, Ercal, Baris, Chang, YingJu, Martin, Shannon E., Graham, Mark J., Patti, Gary J., Han, Xianlin, Crawford, Peter A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124396/
https://ncbi.nlm.nih.gov/pubmed/29925686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99762
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