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Syncytin 1, CD9, and CD47 regulating cell fusion to form PGCCs associated with cAMP/PKA and JNK signaling pathway

BACKGROUND: We have previously reported the formation of polyploid giant cancer cells (PGCCs) through endoreduplication or cell fusion after cobalt chloride (CoCl(2)) induction. Cell fusion plays an important role in development and disease. However, the underlying molecular mechanism concerning cel...

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Publicat a:Cancer Med
Autors principals: Fei, Fei, Li, Chunyuan, Wang, Xinlu, Du, Jiaxing, Liu, Kai, Li, Bo, Yao, Peiyu, Li, Yuwei, Zhang, Shiwu
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558479/
https://ncbi.nlm.nih.gov/pubmed/31025548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2173
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