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Syncytin 1, CD9, and CD47 regulating cell fusion to form PGCCs associated with cAMP/PKA and JNK signaling pathway

BACKGROUND: We have previously reported the formation of polyploid giant cancer cells (PGCCs) through endoreduplication or cell fusion after cobalt chloride (CoCl(2)) induction. Cell fusion plays an important role in development and disease. However, the underlying molecular mechanism concerning cel...

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Publicado en:Cancer Med
Main Authors: Fei, Fei, Li, Chunyuan, Wang, Xinlu, Du, Jiaxing, Liu, Kai, Li, Bo, Yao, Peiyu, Li, Yuwei, Zhang, Shiwu
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558479/
https://ncbi.nlm.nih.gov/pubmed/31025548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2173
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