Combining evidence from four immune cell types identifies DNA methylation patterns that implicate functionally distinct pathways during Multiple Sclerosis progression

BACKGROUND: Multiple Sclerosis (MS) is a chronic inflammatory disease and a leading cause of progressive neurological disability among young adults. DNA methylation, which intersects genes and environment to control cellular functions on a molecular level, may provide insights into MS pathogenesis....

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Udgivet i:EBioMedicine
Main Authors: Ewing, Ewoud, Kular, Lara, Fernandes, Sunjay J., Karathanasis, Nestoras, Lagani, Vincenzo, Ruhrmann, Sabrina, Tsamardinos, Ioannis, Tegner, Jesper, Piehl, Fredrik, Gomez-Cabrero, David, Jagodic, Maja
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Research paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558224/
https://ncbi.nlm.nih.gov/pubmed/31053557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.04.042
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