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Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

Abstract Background Due to limited access to brain tissue, the precise mechanisms underlying neuro-axonal dysfunction in neurological disorders such as multiple sclerosis (MS) are largely unknown. In that context, profiling DNA methylation, which is a stable and cell type-specific regulatory epigene...

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Detalhes bibliográficos
Main Authors: Lara Kular, Maria Needhamsen, Milena Z. Adzemovic, Tatiana Kramarova, David Gomez-Cabrero, Ewoud Ewing, Eliane Piket, Jesper Tegnér, Stephan Beck, Fredrik Piehl, Lou Brundin, Maja Jagodic
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-05-01
Colecção:Clinical Epigenetics
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Acesso em linha:http://link.springer.com/article/10.1186/s13148-019-0678-1
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