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Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis
Abstract Background Due to limited access to brain tissue, the precise mechanisms underlying neuro-axonal dysfunction in neurological disorders such as multiple sclerosis (MS) are largely unknown. In that context, profiling DNA methylation, which is a stable and cell type-specific regulatory epigene...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BMC
2019-05-01
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Colecção: | Clinical Epigenetics |
Assuntos: | |
Acesso em linha: | http://link.springer.com/article/10.1186/s13148-019-0678-1 |
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