Non-parametric combination analysis of multiple data types enables detection of novel regulatory mechanisms in T cells of multiple sclerosis patients

Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system with prominent neurodegenerative components. The triggering and progression of MS is associated with transcriptional and epigenetic alterations in several tissues, including peripheral blood. The combined influence of tra...

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Published in:Sci Rep
Main Authors: Fernandes, Sunjay Jude, Morikawa, Hiromasa, Ewing, Ewoud, Ruhrmann, Sabrina, Joshi, Rubin Narayan, Lagani, Vincenzo, Karathanasis, Nestoras, Khademi, Mohsen, Planell, Nuria, Schmidt, Angelika, Tsamardinos, Ioannis, Olsson, Tomas, Piehl, Fredrik, Kockum, Ingrid, Jagodic, Maja, Tegnér, Jesper, Gomez-Cabrero, David
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700160/
https://ncbi.nlm.nih.gov/pubmed/31427643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48493-7
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