Non-parametric combination analysis of multiple data types enables detection of novel regulatory mechanisms in T cells of multiple sclerosis patients

Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system with prominent neurodegenerative components. The triggering and progression of MS is associated with transcriptional and epigenetic alterations in several tissues, including peripheral blood. The combined influence of tra...

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Vydáno v:Sci Rep
Hlavní autoři: Fernandes, Sunjay Jude, Morikawa, Hiromasa, Ewing, Ewoud, Ruhrmann, Sabrina, Joshi, Rubin Narayan, Lagani, Vincenzo, Karathanasis, Nestoras, Khademi, Mohsen, Planell, Nuria, Schmidt, Angelika, Tsamardinos, Ioannis, Olsson, Tomas, Piehl, Fredrik, Kockum, Ingrid, Jagodic, Maja, Tegnér, Jesper, Gomez-Cabrero, David
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700160/
https://ncbi.nlm.nih.gov/pubmed/31427643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48493-7
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