PD/1-PD-Ls Checkpoint: Insight on the Potential Role of NK Cells

The identification of inhibitory NK cell receptors specific for HLA-I molecules (KIRs and NKG2A) provided the molecular basis for clarifying the mechanism by which NK cells kill transformed cells while sparing normal cells. The direct interactions between inhibitory NK cell receptors and their HLA-I...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Pesce, Silvia, Greppi, Marco, Grossi, Francesco, Del Zotto, Genny, Moretta, Lorenzo, Sivori, Simona, Genova, Carlo, Marcenaro, Emanuela
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557993/
https://ncbi.nlm.nih.gov/pubmed/31214193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01242
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