PD/1-PD-Ls Checkpoint: Insight on the Potential Role of NK Cells

The identification of inhibitory NK cell receptors specific for HLA-I molecules (KIRs and NKG2A) provided the molecular basis for clarifying the mechanism by which NK cells kill transformed cells while sparing normal cells. The direct interactions between inhibitory NK cell receptors and their HLA-I...

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Vydáno v:Front Immunol
Hlavní autoři: Pesce, Silvia, Greppi, Marco, Grossi, Francesco, Del Zotto, Genny, Moretta, Lorenzo, Sivori, Simona, Genova, Carlo, Marcenaro, Emanuela
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557993/
https://ncbi.nlm.nih.gov/pubmed/31214193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01242
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