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Human NK cells: surface receptors, inhibitory checkpoints, and translational applications

NK cells play important roles in innate defenses against viruses and in the control of tumor growth and metastasis. The regulation/induction of NK cell function is mediated by an array of activating or inhibitory surface receptors. In humans, major activating receptors involved in target cell killin...

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Bibliografiske detaljer
Udgivet i:Cell Mol Immunol
Main Authors: Sivori, Simona, Vacca, Paola, Del Zotto, Genny, Munari, Enrico, Mingari, Maria Cristina, Moretta, Lorenzo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474200/
https://ncbi.nlm.nih.gov/pubmed/30778167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-019-0206-4
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