PD/1-PD-Ls Checkpoint: Insight on the Potential Role of NK Cells

The identification of inhibitory NK cell receptors specific for HLA-I molecules (KIRs and NKG2A) provided the molecular basis for clarifying the mechanism by which NK cells kill transformed cells while sparing normal cells. The direct interactions between inhibitory NK cell receptors and their HLA-I...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Pesce, Silvia, Greppi, Marco, Grossi, Francesco, Del Zotto, Genny, Moretta, Lorenzo, Sivori, Simona, Genova, Carlo, Marcenaro, Emanuela
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557993/
https://ncbi.nlm.nih.gov/pubmed/31214193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01242
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