Rif1 S-acylation mediates DNA double-strand break repair at the inner nuclear membrane

Rif1 is involved in telomere homeostasis, DNA replication timing, and DNA double-strand break (DSB) repair pathway choice from yeast to human. The molecular mechanisms that enable Rif1 to fulfill its diverse roles remain to be determined. Here, we demonstrate that Rif1 is S-acylated within its conse...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Fontana, Gabriele A., Hess, Daniel, Reinert, Julia K., Mattarocci, Stefano, Falquet, Benoît, Klein, Dominique, Shore, David, Thomä, Nicolas H., Rass, Ulrich
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557901/
https://ncbi.nlm.nih.gov/pubmed/31182712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10349-z
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